The increasing prevalence of Cyber-Physical Systems and the Internet of Things (CPS-IoT) applications and Foundation Models are enabling new applications that leverage real-time control of the environment. For example, real-time control of Heating, Ventilation and Air-Conditioning (HVAC) systems can reduce its usage when not needed for the comfort of human occupants, hence reducing energy consumption. Collecting real-time feedback on human preferences in such human-in-the-loop (HITL) systems, however, is difficult in practice. We propose the use of large language models (LLMs) to deal with the challenges of dynamic environments and difficult-to-obtain data in CPS optimization. In this paper, we present a case study that employs LLM agents to mimic the behaviors and thermal preferences of various population groups (e.g. young families, the elderly) in a shopping mall. The aggregated thermal preferences are integrated into an agent-in-the-loop based reinforcement learning algorithm AitL-RL, which employs the LLM as a dynamic simulation of the physical environment to learn how to balance between energy savings and occupant comfort. Our results show that LLMs are capable of simulating complex population movements within large open spaces. Besides, AitL-RL demonstrates superior performance compared to the popular existing policy of set point control, suggesting that adaptive and personalized decision-making is critical for efficient optimization in CPS-IoT applications. Through this case study, we demonstrate the potential of integrating advanced Foundation Models like LLMs into CPS-IoT to enhance system adaptability and efficiency. The project's code can be found on our GitHub repository.

Large language models (LLMs) have the potential to transform our lives and work through the content they generate, known as AI-Generated Content (AIGC). To harness this transformation, we need to understand the limitations of LLMs. Here, we investigate the bias of AIGC produced by seven representative LLMs, including ChatGPT and LLaMA. We collect news articles from The New York Times and Reuters, both known for their dedication to provide unbiased news. We then apply each examined LLM to generate news content with headlines of these news articles as prompts, and evaluate the gender and racial biases of the AIGC produced by the LLM by comparing the AIGC and the original news articles. We further analyze the gender bias of each LLM under biased prompts by adding gender-biased messages to prompts constructed from these news headlines. Our study reveals that the AIGC produced by each examined LLM demonstrates substantial gender and racial biases. Moreover, the AIGC generated by each LLM exhibits notable discrimination against females and individuals of the Black race. Among the LLMs, the AIGC generated by ChatGPT demonstrates the lowest level of bias, and ChatGPT is the sole model capable of declining content generation when provided with biased prompts.

Automated machine learning (AutoML) algorithms have grown in popularity due to their high performance and flexibility to adapt to different problems and data sets. With the increasing number of AutoML algorithms, deciding which would best suit a given problem becomes increasingly more work. Therefore, it is essential to use complex and challenging benchmarks which would be able to differentiate the AutoML algorithms from each other. This paper compares the performance of four different AutoML algorithms: Tree-based Pipeline Optimization Tool (TPOT), Auto-Sklearn, Auto-Sklearn 2, and H2O AutoML. We use the Diverse and Generative ML benchmark (DIGEN), a diverse set of synthetic datasets derived from generative functions designed to highlight the strengths and weaknesses of the performance of common machine learning algorithms. We confirm that AutoML can identify pipelines that perform well on all included datasets. Most AutoML algorithms performed similarly; however, there were some differences depending on the specific dataset and metric used.

The standard way to estimate the parameters $\Theta_\text{SEIR}$ (e.g., the transmission rate $\beta$) of an SEIR model is to use grid search, where simulations are performed on each set of parameters, and the parameter set leading to the least $L_2$ distance between predicted number of infections and observed infections is selected. This brute-force strategy is not only time consuming, as simulations are slow when the population is large, but also inaccurate, since it is impossible to enumerate all parameter combinations. To address these issues, in this paper, we propose to transform the non-differentiable problem of finding optimal $\Theta_\text{SEIR}$ to a differentiable one, where we first train a recurrent net to fit a small number of simulation data. Next, based on this recurrent net that is able to generalize SEIR simulations, we are able to transform the objective to a differentiable one with respect to $\Theta_\text{SEIR}$, and straightforwardly obtain its optimal value. The proposed strategy is both time efficient as it only relies on a small number of SEIR simulations, and accurate as we are able to find the optimal $\Theta_\text{SEIR}$ based on the differentiable objective. On two COVID-19 datasets, we observe that the proposed strategy leads to significantly better parameter estimations with a smaller number of simulations.

Artificial Intelligence (AI) promises to uplift our ability to profile, predict, promote and protect human health in many exciting ways. But eagerness in the health system to ardently embrace AI should not blind us to potential pitfalls. Lest we lament, as Othello did about Desdemona, that we "loved too well but not wisely". Human health is configured by intricate interactions between several complex systems--biological, physical and social environments being the foremost. Alongside is the layered labyrinth of the health system that serves our health needs.

In this paper, we propose a new framework for mitigating biases in machine learning systems. The problem of the existing mitigation approaches is that they are model-oriented in the sense that they focus on tuning the training algorithms to produce fair results, while overlooking the fact that the training data can itself be the main reason for biased outcomes. Technically speaking, two essential limitations can be found in such model-based approaches: 1) the mitigation cannot be achieved without degrading the accuracy of the machine learning models, and 2) when the data used for training are largely biased, the training time automatically increases so as to find suitable learning parameters that help produce fair results. To address these shortcomings, we propose in this work a new framework that can largely mitigate the biases and discriminations in machine learning systems while at the same time enhancing the prediction accuracy of these systems. The proposed framework is based on conditional Generative Adversarial Networks (cGANs), which are used to generate new synthetic fair data with selective properties from the original data. We also propose a framework for analyzing data biases, which is important for understanding the amount and type of data that need to be synthetically sampled and labeled for each population group. Experimental results show that the proposed solution can efficiently mitigate different types of biases, while at the same time enhancing the prediction accuracy of the underlying machine learning model.

The understanding of variations in genome sequences assists us in identifying people who are predisposed to common diseases, solving rare diseases, and finding the corresponding population group of the individuals from a larger population group. Although classical machine learning techniques allow researchers to identify groups (i.e. clusters) of related variables, the accuracy, and effectiveness of these methods diminish for large and high-dimensional datasets such as the whole human genome. On the other hand, deep neural network architectures (the core of deep learning) can better exploit large-scale datasets to build complex models. In this paper, we use the K-means clustering approach for scalable genomic data analysis aiming towards clustering genotypic variants at the population scale. Finally, we train a deep belief network (DBN) for predicting the geographic ethnicity. We used the genotype data from the 1000 Genomes Project, which covers the result of genome sequencing for 2504 individuals from 26 different ethnic origins and comprises 84 million variants. Our experimental results, with a focus on accuracy and scalability, show the effectiveness and superiority compared to the state-of-the-art.

Deep learning techniques can be used to extract facial imaging biomarkers of human health status and to track the effects of cosmetic interventions. At the Deep Learning in Healthcare Summit, Research Scientist, Anastasia Georgievskaya from Beauty.AI, will be presenting a set of tools for analysis of perception of human age and health status. She will also demonstrate that when certain population groups are under-represented in the training sets, these populations are left out or may be subject to higher error rates. This is why Youth Laboratories launched Diversity.AI, a think tank for anti-discrimination by the deep-learned systems. The presentation describes the strategies for evaluating human appearance for machine-human interaction and reveals the risks and dangers of deep-learned biomarkers.